Publications

31. “β‐Selective Aroylation of Activated Alkenes by Photoredox Catalysis” Lei, Z.; Banerjee, A.; Kusevska, E.; Liu, P.*; Ngai, M.-Y.* Angew. Chem. Int. Ed. 2019, 58, 7318.

30. “Synthesis of Tri‐ and Difluoromethoxylated Compounds via Visible Light Photoredox Catalysis” Lee, J. W.; Lee, K. N.; Ngai, M.-Y.* Angew. Chem. Int. Ed. 2019, 58, 11171.

29. “Catalytic Radical Difluoromethoxylation of Arenes and Heteroarenes” Lee, J. W.; Zheng, W.; Morales-Rivera, C. A.; Liu, P.*; Ngai, M.-Y.* Chem. Sci. 2019, 10, 3217. (Selected as Chemical Science HOT Article)

• Highlighted in ChemistryView, 2019.
• Highlighted in Synfacts, 2019, 15, 0520.

28. “Acyl Radical Chemistry via Visible-Light Photoredox Catalysis” Banerjee, A; Lei, Zhen; Ngai, M.-Y.* Synthesis 2019, 51, 303. (Invited Review by Professor Dieter Enders).

• Selected as the Cover of the Issue.

27. “Recent Development of Catalytic Trifluoromethoxylation Reactions” Lee, K. N.; Lee, J. W.; Ngai, M.-Y.* Tetrahedron 2018, 74, 7127. (Invited Review for Tetrahedron Symposium in Organo Fluorine Chemistry).

26. “Redox‐Active Reagents for Photocatalytic Generation of the OCF3 Radical and (Hetero)Aryl C−H Trifluoromethoxylation” Zheng, W.; Lee, J. W.; Morales-Rivera, C. A.; Liu, P.*; Ngai, M.-Y.* Angew. Chem. Int. Ed. 2018, 57, 13795.

25. “Transition-Metal-Free C–H Amidation and Chlorination: Synthesis of N/N′-Mono-Substituted Imidazopyridin-2-ones from N-Pyridyl-N-Hydroxylamine Intermediates” Lee, K. N.; Spiegowski, D. N.; Lee, J. W.; Lim, S.; Zhao, F; Ngai, M.-Y.* Chem. Commun. 2018, 54, 6935. (Emerging Investigators Issue 2018) 

24. “Catalytic C−H Trifluoromethoxylation of Arenes and Heteroarenes” Zheng, W.; Morales-Rivera, C. A.; Lee, J. W.; Liu, P.*; Ngai, M.-Y.* Angew. Chem. Int. Ed. 2018, 57, 9645. (Accepted as Very Important Paper)

• Highlighted in Angew. Chem. Int. Ed. 2018, 57, 7942.

23. “Recent Developments in Transition-Metal Photoredox-Catalysed Reactions of Carbonyl Derivatives” Lee, K. N.; Ngai, M.-Y.* Chem. Commun. 2017, 53, 13093.

22. “Selective C–O Bond Formation via a Photocatalytic Radical Coupling Strategy: Access to Perfluoroalkoxylated (ORF) Arenes and Heteroarenes” Lee, J. W.; Spiegowski, D. N.; Ngai, M.-Y.* Chem. Sci. 2017, 8, 6066.

• Highlighted in Synfacts, 2017, 13, 1142.

21. “β-Selective Reductive Coupling of Alkenylpyridines with Aldehydes and Imines via Synergistic Lewis Acid/Photoredox Catalysis” Lee, K. N.; Lei, Z.;  Ngai, M.-Y.* J. Am. Chem. Soc., 2017, 139, 5003.

20. “Development of [18F]Maleimide-Based Glycogen Synthase Kinase-3β Ligands for Positron Emission Tomography Imaging” Hu, K; Patnaik, D.; Collier, T.; Lee, K. N.; Gao, H.; Swoyer, M.; Rotstein, B.; Krishnan, H.; Liang, S.; Wang, J.; Yan, Z.; Hooker, J.; Vasdev, N.; Haggarty, S.;  Ngai, M.-Y.* ACS Med. Chem. Lett., 2017, 8, 287.

19. “Mechanistic Studies on Intramolecular C-H Trifluoromethoxylation of (Hetero)arenes via OCF3-Migration” Lee, K. N.; Lei, Z.; Morales-Rivera, A. C.; Liu, P.; Ngai, M.-Y.* Org. Biomol. Chem., 2016, 14, 5599. (Invited article, New Talent Themed Issue)

18. “Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives” Feng, P.; Ngai, M.-Y.* J. Vis. Exp. 2016, 107. (Invited article)

17. “Synthesis of Trifluoromethoxylated (Hetero)Arenes via OCF3 Migration” Lee, K. N.; Lee, J. W.; Ngai, M.-Y.* Synlett. 2016, 27, 313. (Invited Review Article)

16. “Access to a New Class of Synthetic Building Blocks via Trifluoromethoxylation of Pyridines and Pyrimidines” Feng. P.; Lee, K. N.; Lee, J. W.; Zhan, C.; Ngai, M.-Y.* Chem. Sci. 2016, 7, 424.

• Top 50 Articles of 2016: Organic Chemistry (50 most downloaded Chemical Science articles of 2016).
• Highlighted in Org. Process Res. Dev., 2015, 19, 1918.

15. “A Highly Convergent Total Synthesis of Leustroducsin B” Trost, B. M.; Biannic, B.; Brindle, C. S.; O’Keefe, B. M.; Hunter, T. J.; Ngai, M.-Y. J. Am. Chem. Soc. 2015, 137, 11594.

14. “Trifluoromethoxylation of Arenes: Synthesis of ortho-Trifluoromethoxylated Aniline Derivatives by OCF3-Migration” Hojczyk, K. N.; Feng, P.; Zhan, C.; Ngai, M.-Y.* Angew. Chem. Int. Ed. 2014, 53, 14559.

13. “Pd-Catalyzed Aryl C-H Imidation with Arene as the Limiting Reagent” Boursalian, G. B.; Ngai, M.-Y.; Hojczyk, K. N.; Ritter, T. J. Am. Chem. Soc. 2013, 36, 13278. 

12. “Ligand Accelerated Enantioselective Propargylation of Aldehydes via Allenylzinc Reagents” Trost, B. M.; Ngai, M.-Y.; Dong, G.-B. Org. Lett. 2011, 13, 1900.

11. “Enantioselective Iridium Catalyzed Carbonyl Allylation From the Alcohol or Aldehyde Oxidation Level via Transfer Hydrogenative Coupling of Allyl Acetate” Kim, I.-S.; Ngai, M.-Y.; Krische, M. J. J. Am. Chem. Soc. 2008, 130, 14891.

10. “Ruthenium Catalyzed C-C Bond Forming Transfer Hydrogenation: Reductive Coupling of Allenes to Paraformaldehy

9. “Enantioselective C-H Allylation of Alcohols Employing Allyl Acetate: Iridium Catalyzed Carbonyl Allylation from the Alcohol Oxidation Level” Kim, I.-S.; Ngai, M.-Y.; Krische, M. J. J. Am. Chem. Soc. 2008, 130, 6340.

• Highlighted in Chemical & Engineering News 2008, 86(19), 10.

8. “Enantioselective Iridium Catalyzed Imine Vinylation: Optically Enriched Allylic Amines via Alkyne-Imine Reductive Coupling Mediated by Hydrogen,” Ngai, M.-Y.; Barchuk, A.; Krische, M. J. J. Am. Chem. Soc. 2007, 129, 12644.

7. “Enantiomerically Enriched Allylic Alcohols and Allylic Amines via C-C Bond Forming Hydrogenation: Asymmetric Carbonyl and Imine Vinylation” Skucas, E.; Ngai, M.-Y.; Komanduri V.; .Krische, M. J. Acc. Chem. Res. 2007, 40, 1394.

6. “Allylic Amines via Iridium Catalyzed C-C Bond Forming Hydrogenation: Imine Vinlyation in the Absence of Stoichiometric Byproducts or Metallic Reagents” Barchuk, A.; Ngai, M.-Y.; Krische, M. J. J. Am. Chem. Soc. 2007, 129, 8432.

5. “Hydrogen-Mediated C-C Bond Formation: A Broad New Concept in Catalytic C-C Coupling” Ngai, M.-Y.; Kong, J.-R.; Krische, M. J. J. Org. Chem. 2007, 72, 1063. 

• The 3rd Most-Cited Article Published in 2007.

4. “Iridium Catalyzed C-C Bond Forming Hydrogenation: Direct Regioselective Reductive Coupling of Alkyl-Substituted Alkynes to Activated Ketones” Ngai, M.-Y.; Barchuk, A.; Krische, M. J. J. Am. Chem. Soc. 2007, 129, 280.

3. “Lessons in Green Chemistry from the Smallest of Molecules: C-C Bond Formation via Catalytic Hydrogenation” Ngai, M.-Y.; Krische, M. J. Chim. Oggi/Chemistry Today 2006,24, 12.

2. “Highly Enantioselective Direct Reductive Coupling of Conjugated Alkynes and a-Ketoesters via Rhodium-Catalyzed Asymmetric Hydrogenation” Kong, J.-R.; Ngai, M.-Y.; Krische, M. J. J. Am. Chem. Soc. 2006, 128, 718.

1. “[(O^N^N)PtX] Complexes as a New Class of Light-Emitting Materials for Electrophosphorescent Devices” Kwok, C.-C.; Ngai, M.-Y.; Chan, S.-C.; Sham, I. H. T.; Che, C.-M.;Zhu, N. Inorg. Chem. 2005, 44, 4442.